Prep HPLC Column, RP C4, 5um, 100A. 21.2mm ID x 150mm Length. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Cogent RP C4™ is a reversed-phase HPLC stationary phase designed for the purification and isolation of hydrophobic and neutral compounds. Manufactured using a four-carbon butyl ligand bonded to ultra-high purity silica and fully double end capped, this stationary phase provides reproducible chromatographic performance and reduced hydrophobic retention compared to C8 and C18 phases. The chemistry is particularly useful for preparative-scale separations where efficient recovery and purification of target compounds are required.
68504-P21-150 is a preparative HPLC column packed with 5 µm RP C4™ particles featuring a 100 Å pore size in a 21.2 mm ID x 150 mm format. The large internal diameter provides substantial sample loading capacity, while the increased 150 mm column length delivers enhanced resolution and peak capacity compared to shorter preparative columns. The 5 µm particles provide lower operating backpressure than smaller particle sizes, making the column well suited for preparative HPLC systems. Typical operating flow rates are approximately 15–30 mL/min depending on mobile phase composition, analyte characteristics, and system capabilities.
This column is particularly useful for the purification of hydrophobic and neutral compounds in pharmaceutical, chemical, and research laboratories. Compared to C8 and C18 phases, the C4 bonded phase generally provides lower retention, which can improve recovery and reduce purification cycle times. The 21.2 mm ID format is ideal for preparative applications requiring higher sample loading capacity and efficient fraction collection. A specialized preparative HPLC system is required for operation.
Key Benefits
RP C4™ stationary phase
USP L26 equivalent chemistry
Butyl (C4) bonded phase
Fully double end capped
Ultra-high purity silica support
Lower retention than C8 phases
High sample loading capacity
Lower operating backpressure than smaller particles
5 µm particle size
Optimized for preparative HPLC
Typical Applications
Preparative HPLC
Compound purification
Fraction collection
Pharmaceutical purification
Hydrophobic compound purification
Neutral compound purification
Process development
Method development
Research and development
Laboratory-scale production
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: RP C4™
USP Classification: L26
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 21.2 mm ID x 150 mm
Length: 150 mm
Typical Flow Rate: 15–30 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Designed for preparative purification of hydrophobic and neutral compounds
Provides less retention than C8 stationary phases
High loading capacity for preparative-scale applications
The 21.2 mm ID format requires a specialized preparative HPLC system
Typical operating flow rates are approximately 15–30 mL/min
5 µm particles provide lower operating backpressure and robust performance
Fully double end capped to minimize secondary interactions
The 150 mm length provides increased resolution and peak capacity compared to shorter preparative columns
Excellent choice for preparative purification and fraction collection
This is a Special Order Item